Dupixent (dupilumab) is a brand-name subcutaneous injection that’s prescribed for atopic dermatitis, asthma, and more. It works to treat those conditions by blocking proteins that cause inflammation.
Dupixent blocks two proteins called interleukins that can cause inflammation in your body. By blocking these proteins, Dupixent reduces inflammation. This can make symptoms of your condition more manageable.
For atopic dermatitis
If you have atopic dermatitis, your immune system causes inflammation under your skin. When this inflammation flares up, it can cause a dry, itchy rash on your skin. Dupixent reduces the inflammation. This helps relieve your symptoms and makes your skin clearer.
For asthma
If you have moderate to severe asthma, your lungs may have more inflammation than the lungs of someone without asthma. This can lead to coughing, wheezing, or difficulty breathing.
Dupixent lowers the inflammation in your lungs. It can also help some people with asthma depend less on corticosteroid medications to treat their symptoms. Some might stop needing to use steroids for asthma altogether.
However, you should not stop or reduce your steroid medication on your own. Your doctor will help determine the treatment plan that fits your needs.
For eosinophilic esophagitis
If you have eosinophilic esophagitis, your immune system causes chronic inflammation and swelling in your esophagus. (The esophagus is a tube connecting your mouth and stomach). This can lead to difficulty swallowing, heartburn, nausea, vomiting, and other symptoms.
Dupixent reduces inflammation in your body, including in your esophagus. This decreases the swelling in your esophagus, which helps relieve your symptoms.
For chronic rhinosinusitis with nasal polyps
If you have chronic rhinosinusitis with nasal polyps, you usually have long-term inflammation in your nose and sinuses. This swelling often causes congestion and difficulty breathing. Dupixent reduces the swelling in your nose and sinuses.
For prurigo nodularis
If you have prurigo nodularis, you may have hard skin bumps and intense itchiness. The exact cause of this condition remains unknown. But experts think the symptoms involve unusual function of the immune system.
Dupixent begins to work after you’ve had your first injection. However, it may take some weeks to months before you notice relief from your condition.
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